Recurrent severe hypophosphatemia following intravenous iron administration

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Intravenous Iron Administration and Hypophosphatemia in Clinical Practice

Introduction. Parenteral iron formulations are frequently used to correct iron deficiency anemia (IDA) and iron deficiency (ID). Intravenous formulation efficacy on ferritin and hemoglobin level improvement is greater than that of oral formulations while they are associated with lower gastrointestinal side effects. Ferric carboxymaltose- (FCM-) related hypophosphatemia is frequent and appears w...

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Severe hypophosphataemia after intravenous iron administration

Currently, in many centres, intravenous administration of iron is becoming increasingly popular because of higher efficacy and decreased side effects, mainly gastrointestinal, compared with oral iron therapy. Studies of intravenous ferric carboxymaltose administration in the postpartum setting and in patients with non-dialysis-dependent chronic kidney disease revealed a decrease in serum phosph...

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Severe Hypophosphatemia Following Denosumab Administration in a Hemodialysis Patient with Progressive Prostate Cancer

In a 68-year-old man on maintenance hemodialysis (HD), severe anemia was detected. Bone marrow biopsy was performed for investigation of pancytopenia and pathological examination revealed adenocarcinoma of the prostate. Prostate specific antigen (PSA) was 574 ng/mL. After androgen deprivation therapy was initiated, PSA decreased to 13.7 ng/mL. But subsequent elevation of PSA and pain due to bon...

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Choice of High-Dose Intravenous Iron Preparation Determines Hypophosphatemia Risk

BACKGROUND Ferric carboxymaltose (FCM) and iron isomaltoside 1000 (IIM) are increasingly used because they allow correction of severe iron deficiency in a single infusion. A transient decrease in serum phosphate concentrations is a frequent side effect of FCM. AIM To characterize this adverse event and search for its predictors in a gastroenterology clinic patient cohort. METHODS Electronic...

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Pharmacokinetics of Cefepime Following Intravenous and Intramuscular Administration in Sheep

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ژورنال

عنوان ژورنال: Clinical Case Reports

سال: 2020

ISSN: 2050-0904,2050-0904

DOI: 10.1002/ccr3.2595